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Time Lapse Imaging System BioStation IM-Q

Long-term, time-lapse imaging without focus drift

Hematopoietic differentiation of hES cells


Widefield image (3×3)

Time-lapse movie showing morphological changes from day 0 to day 28 (hematopoietic differentiation of hES cells). The images were taken in combination with perfusion components at 10x magnification every 8 minutes for 4 weeks.

  • Courtesy of Dr. Akira Niwa, Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University

Long-term time-lapse observation of rat hippocampal neurons

Membrane-anchored GFP of rat hippocampal neurons was captured in 120-hour time-lapse imaging.

  • Courtesy of Dr. Chieko Nakada, Dr. Yuuri Nemoto, Dr. Hiroko Hijikata, Dr. Akihiro Kusumi, Institute for Integrated Cell-Material Sciences, Kyoto University

Time-lapse observation of fertilized mouse embryo up to the blastocyst stage

Time-lapse observation of fertilized mouse embryo up to the blastocyst stage for a total 105 hours. During observation, medium is replaced with blastocyst medium.
40x (before medium replacement)
80x (after medium replacement)

  • Courtesy of Ronny Janssens, Centrum voor Reproductieve Geneeskunde, Laboratorium IVF, Z-VUB Brussels

Scratch assays of MDCK cells

Scratch assays of MDCK cells, at 20x magnification every one minute for 3 hours.

  • Courtesy of Laurence Mery, INSERM, Universite Paris-Sud Orsay, France (Journal of Cell Science 123, 1449-1459)

Colonization of mouse iPS cells

Colonization of mouse iPS cells initiated with Oct4, Sox2, cMyc, Klf4 genes, at 20x magnification every 10 minutes for 60 hours on the MEF feeder.

  • Courtesy of System BioScience Inc.